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What is the ld50 of dioxin?

Asked by: Donato Ordiñana

asked in category: General Last Updated: 22nd April, 2020

What is the ld50 of dioxin?

LD50 is the abbreviation used for the dose which kills 50% of the test population. The LD50 for dioxin is 0.02 mg/kg of body weight for a rat and 0.001 mg/kg of body weight for a dog, i.e. the rat is twenty times more tolerant than the dog.

Accordingly, how much dioxin is lethal?

LD 50 stands for “lethal dose—50 percent.” That is, the LD 50 for a substance is the amount of that substance needed to kill onehalf of a test population of animals in some given period of time, usually a few days. The LD 50 for TCDD for guinea pigs is 0.0006 mg/kg (milligrams per kilogram).

Similarly, can dioxin kill you? “The lethal dose of dioxin in humans isn’t known because there has been no previous case I am aware of,” says Alastair Hay, a toxicologist and chemical weapons expert at Leeds University. “Most other examples of dioxin poisoning come from skin contact through industrial accidents or occupational exposure.”

In this regard, what is ld50 used for?

The median lethal dose (or LD50) is defined as the dose of a test substance that is lethal for 50% of the animals in a dose group. LD50 values have been used to compare relative acute hazards of industrial chemicals, especially when no other toxicology data are available for the chemicals.

Which chemical is the most toxic based on its ld50?

So here is a list of substances that are more poisonous than their LD50 values might indicate.

  1. Botulinum toxins. Even though some of them are used in the cosmetic industry (including in botox), the botulinum family of neurotoxins includes the most toxic substances known to man.
  2. Snake toxins.
  3. Arsenic.
  4. Polonium-210.
  5. Mercury.
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